Physician Assistant Salary in St. Louis
2026 compensation data for Physician Assistant positions in St. Louis, MO. Ranges from $78,000 (entry-level) to $152,000 (senior). Median: $109,000.
Median (Mid)
$109,000
$52.4/hr
vs National
+0%
US: $109,000
COL Index
92
vs US avg = 100
Senior Max
$152,000
Top of band
Salary Ranges by Experience Level
Detailed Compensation Breakdown
| Level | Annual Min | Annual Median | Annual Max | Hourly (Median) |
|---|---|---|---|---|
| Entry-Level (0–2 yrs) | $78,000 | $88,000 | $101,000 | $42.31/hr |
| Mid-Level (3–5 yrs) | $97,000 | $109,000 | $124,000 | $52.4/hr |
| Senior (6+ yrs) | $118,000 | $133,000 | $152,000 | $63.94/hr |
What Your Salary Is Really Worth in St. Louis
A mid-level physician assistant earning $109,000 in St. Louis has the same buying power as $118,000 in an average US city, after adjusting for the local cost of living (COL index 92).
Cost of living comparisons use a base of 100 (US national average). Higher index = higher housing, transport, and consumer prices.
About Physician Assistant Salaries in St. Louis
The median physician assistant salary in St. Louis, MO is $109,000 for mid-level professionals, which is 0% above the national median. With a cost of living index of 92 (national average = 100), St. Louis offers an affordable cost of living, making these salaries stretch further.
Entry-level physician assistants in St. Louis can expect to earn between $78,000 and $101,000 (about $42.31/hour), while senior professionals with 6+ years of experience earn up to $152,000 ($152K annually, or about $73.08/hour).
These figures represent base salary only and do not include bonuses, equity, or benefits, which can add 20–50% to total compensation — especially at technology companies and in competitive markets like St. Louis.
Frequently Asked Questions: Physician Assistant Salary in St. Louis
What is the average Physician Assistant salary in St. Louis?+
The average Physician Assistant salary in St. Louis is $109,000 for a mid-level professional (3–5 years of experience). Entry-level pay starts around $88,000 and senior-level pay reaches $133,000.
How much does an entry-level physician assistant make in St. Louis?+
Entry-level physician assistants in St. Louis earn between $78,000 and $101,000, with a median of $88,000 per year (about $42.31/hour).
What is the hourly rate for a Physician Assistant in St. Louis?+
Based on a 2,080-hour work year, a Physician Assistant in St. Louis earns roughly $42.31/hour at entry-level, $52.4/hour at mid-level, and $63.94/hour at senior-level.
Is the Physician Assistant salary in St. Louis higher than the US average?+
Yes — Physician Assistant salaries in St. Louis are about 0% higher than the US national median of $109,000.
Does this include bonuses or equity?+
No — these figures are base salary only. Total compensation (base + bonus + equity + benefits) is typically 20–50% higher, and can be 2–3x at top technology and finance employers.
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