Physician Assistant Salary in San Francisco
2026 compensation data for Physician Assistant positions in San Francisco, CA. Ranges from $115,000 (entry-level) to $223,000 (senior). Median: $159,000.
Median (Mid)
$159,000
$76.44/hr
vs National
+0%
US: $159,000
COL Index
180
vs US avg = 100
Senior Max
$223,000
Top of band
Salary Ranges by Experience Level
Detailed Compensation Breakdown
| Level | Annual Min | Annual Median | Annual Max | Hourly (Median) |
|---|---|---|---|---|
| Entry-Level (0–2 yrs) | $115,000 | $130,000 | $149,000 | $62.5/hr |
| Mid-Level (3–5 yrs) | $142,000 | $159,000 | $182,000 | $76.44/hr |
| Senior (6+ yrs) | $173,000 | $196,000 | $223,000 | $94.23/hr |
What Your Salary Is Really Worth in San Francisco
A mid-level physician assistant earning $159,000 in San Francisco has the same buying power as $88,000 in an average US city, after adjusting for the local cost of living (COL index 180).
Cost of living comparisons use a base of 100 (US national average). Higher index = higher housing, transport, and consumer prices.
About Physician Assistant Salaries in San Francisco
The median physician assistant salary in San Francisco, CA is $159,000 for mid-level professionals, which is 0% above the national median. With a cost of living index of 180 (national average = 100), San Francisco offers a high cost of living that partially offsets the salary premium.
Entry-level physician assistants in San Francisco can expect to earn between $115,000 and $149,000 (about $62.5/hour), while senior professionals with 6+ years of experience earn up to $223,000 ($223K annually, or about $107.21/hour).
These figures represent base salary only and do not include bonuses, equity, or benefits, which can add 20–50% to total compensation — especially at technology companies and in competitive markets like San Francisco.
Frequently Asked Questions: Physician Assistant Salary in San Francisco
What is the average Physician Assistant salary in San Francisco?+
The average Physician Assistant salary in San Francisco is $159,000 for a mid-level professional (3–5 years of experience). Entry-level pay starts around $130,000 and senior-level pay reaches $196,000.
How much does an entry-level physician assistant make in San Francisco?+
Entry-level physician assistants in San Francisco earn between $115,000 and $149,000, with a median of $130,000 per year (about $62.5/hour).
What is the hourly rate for a Physician Assistant in San Francisco?+
Based on a 2,080-hour work year, a Physician Assistant in San Francisco earns roughly $62.5/hour at entry-level, $76.44/hour at mid-level, and $94.23/hour at senior-level.
Is the Physician Assistant salary in San Francisco higher than the US average?+
Yes — Physician Assistant salaries in San Francisco are about 0% higher than the US national median of $159,000.
Does this include bonuses or equity?+
No — these figures are base salary only. Total compensation (base + bonus + equity + benefits) is typically 20–50% higher, and can be 2–3x at top technology and finance employers.
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