Physician Assistant Salary in San Francisco

2026 compensation data for Physician Assistant positions in San Francisco. Ranges from $115,000 (entry-level) to $223,000 (senior).

Median (Mid)

$159,000

vs National

+0%

COL Index

180

Senior Max

$223,000

Salary Ranges by Experience Level

Entry-Level (0–2 years)$115,000$149,000
$115KMedian: $130,000$149K
Mid-Level (3–5 years)$142,000$182,000
$142KMedian: $159,000$182K
Senior (6+ years)$173,000$223,000
$173KMedian: $196,000$223K

Detailed Compensation Breakdown

LevelMinimumMedianMaximum
Entry-Level$115,000$130,000$149,000
Mid-Level$142,000$159,000$182,000
Senior$173,000$196,000$223,000

About Physician Assistant Salaries in San Francisco

The median physician assistant salary in San Francisco is $159,000 for mid-level professionals, which is 0% above the national median. With a cost of living index of 180 (national average = 100), San Francisco offers a higher cost of living that partially offsets the salary premium.

Entry-level physician assistants in San Francisco can expect to earn between $115,000 and $149,000, while senior professionals with 6+ years of experience earn up to $223,000.

These figures represent base salary only and do not include bonuses, equity, or benefits, which can add 20–50% to total compensation — especially at technology companies and in competitive markets.

Physician Assistant Salaries in Other Cities

Other Roles in San Francisco

Know Your Worth as a Physician Assistant in San Francisco

Get personalized salary insights, AI-powered negotiation coaching, and real-time market data — completely free for workers.

Join the Waitlist — It's Free